Induction of Labor, Oxytocin
Conditions
Brief summary
This study evaluates the need of oxytocin therapy in active phase of labor. there will be two groups treating with oxytocin in latent phase.One group will be treated with low dose oxytocin therapy and the other group will be treated with high dose oxytocin therapy. oxytocin treatment will be ceased at the beginning of the active phase of labor. the need of oxytocin treatment in active phase of labor will be compared between two groups.
Detailed description
Oxytocin treatment in active phase of labour is used with respect to clinicians preference and best approach has not been described. We want to investigate the effect of oxytocin treatment by using different regims in latent phase of labor when oxytocin treatment is ceased in active phase of labour. In our trial we discontinued oxytocin in active phase of labour and investigate which group needs oxytocin therapy due to inadequate uterine contractions and arrest of labor.
Interventions
DRUGoxytocin
one group will be treated with low dose oxytocin and the other group will be treated with high dose oxytocin for augmentation of labor induction.
Sponsors
Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Live fetus in cephalic presentation, sonographically estimated fetal weight less than 4200 g, undergoing induction of labor at 37-42 weeks of gestation, having indications of labor, no previous uterine surgery
Exclusion criteria
* malpresentation, placenta previa, previous uterine surgery, multiple gestation, active genital herpes, non-reassuring fetal heart rate pattern
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| need for oxytocin retreatment | an average of one year | need for oxytocin retreatment due to inadequate uterine contractions and labor arrest |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| length of active phase | an average of one year | duration of acive phase of labor |
| ratio of caesarean section | an average of one year | caesaraen section rate in total delivery |
| total oxytocin dose | an average of one year | total amount of oxytocin treatment in latent and active phase of labor |
| APGAR scores | an average of one year | neonatal 1 minute and 5-minute-APGAR scores |
Countries
Turkey (Türkiye)
Outcome results
None listed