Driving Mutations, Epithelial Ovarian Cancer, Epithelial Ovarian Tumor of Borderline Malignancy, Progression-free Survival
Conditions
Brief summary
Epithelial ovarian carcinomatous and borderline components sometimes appeared in one patient. This study aims to analyze the genomic patterns of the carcinomatous and borderline components in the ovarian epithelial tissues. These tissues will be collected from paraffin section by microdissection to distinguish normal, carcinomatous and borderline tissues.
Interventions
None listed
Sponsors
Lei Li
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* Confirmed primary epithelial ovarian borderline tumor with cancer * Signed an approved informed consents * Feasible for sampling
Exclusion criteria
* Not meeting all of the inclusion criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Frequencies of somatic driving mutations | Two years | The differences of frequencies of somatic driving mutations will be compared between normal, carcinomatous and borderline tissues. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Progression-free survival | Five years | Progression-free survival between patients with differential expressed multi-omics will be compared. |
Countries
China
Contacts
Primary ContactLei Li, M.D.
Outcome results
None listed