Nasopharyngeal Airway Facilitate Transnasal Humidified Rapid Insufflation Ventilatory Exchange

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03741998

Enrollment

120

Registered

2018-11-15

Start date

2018-11-07

Completion date

2019-12-30

Last updated

2019-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypercapnia, Hypoxia

Brief summary

For performing transnasal humidified rapid insufflation ventilatory exchange (THRIVE), jaw-thrust maneuver have to maintain to make sure the airway open and the CO2 clearance during apnoea. The objective of present study is to prove that nasopharyngeal airway facilitate THRIVE and no need jaw-thrust maneuver and maintain the similar PO2 and PCO2 during apnoea.

Interventions

DEVICENasopharyngeal airway

THRIVE with a regular nasopharyngeal airway.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Signed informed consent. * Undergoing surgery with general anaesthesia. * Adult, \>18 years old. * American Society of Anesthesiology classification I-II.

Exclusion criteria

* Coagulation disorders or a tendency of nose bleeding * An episode/exacerbation of congestive heart failure (CHF) that requires a change in medication, diet or hospitalization from any cause in the last 6 months * Severe aortic stenosis or mitral stenosis; * Cardiac surgery involving thoracotomy (e.g., coronary artery bypass graft (CABG), valve replacement surgery) in the last 6 months; * Acute myocardial infarction in the last 6 months; * Acute arrhythmia (including both tachycardia and bradycardia) with hemodynamic instability; * Diagnosed COPD or current other acute or chronic lung disease requiring supplemental chronic or intermittent oxygen therapy); * Increased intracranial pressure; * ASA \>II; * Mouth, nose, or throat infection; * Fever, defined as core body temperature \> 37.5°C; * Pregnancy, breastfeeding or positive pregnancy test; * Emergency procedure. * Patient with known or suspected difficult airway

Design outcomes

Primary

Measure	Time frame
The partial pressure of carbon dioxide (pCO2)	From start to end of THRIVE(20 minutes)
The partial pressure of oxygen(PO2)	From start to end of THRIVE(20 minutes)

Countries

China

Contacts

Primary ContactDiansan Su, Dr.

diansansu@yahoo.com+862168383702

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 17, 2026