The Effect of Message Framing on Blood Donation-Study 1

Saving a Life or Preventing a Death: the Effect of Message Framing on Blood Donation Among Rh Negative Donors

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03741413

Enrollment

2074

Registered

2018-11-14

Start date

2018-07-18

Completion date

2018-10-18

Last updated

2020-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rh Negative Blood Donor

Brief summary

Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. On July 18, 2018 blood stockpile of O-negative and B-negative in Guangzhou Blood Center reached the warning line, and we took measures for emergency recruitment. O-negative and B-negative blood donors whose last donation dates were between January 1, 2015 and December 31, 2017 were identified and randomly assigned to three groups. Three different recruitment text messages were send to these groups respectively. At the same time, A-negative and AB-negative blood donors were marked as control group. We observed the re-donation rates among four groups within three months.

Interventions

OTHERGain-frame SMS

Emergency recruitment cell phone short messages that emphasizing donating blood can save patients' lives were sent to donors in this group.

OTHERLoss-frame SMS

Emergency recruitment cell phone short messages emphasizing that donating blood can prevent patients from death were sent to donors in this group.

OTHERControl SMS

Emergency recruitment cell phone short messages that only mentioning the low Rh-negative blood stockpile were sent to donors in this group.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Rh- negative blood donors whose last donations were between January 1, 2015 and December 31, 2017.

Exclusion criteria

* Donors with an obviously invalid phone number. Donors whose serological results of the last donation were positive.

Design outcomes

Primary

Measure	Time frame	Description
Re-donation rate	3 months	Intention-to-treat were applied. Re-donation rate was defined as the number of donors in each group devided by donors who re-donated within 3 months.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026