Lens Diseases
Conditions
Brief summary
Pseudoexfoliation syndrome (PEX) is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye and was first described in 1917 by Lindberg. It is frequently associated with open angle glaucoma, known as pseudoexfoliation glaucoma, which is one of the most common identifiable forms of secondary open angle glaucoma worldwide. Despite extensive research, the exactchemical nature of the fibrillar material is unknown. It is believed to be secreted multifocally in the iris pigment epithelium, the ciliary epithelium, and the peripheral anterior lens epithelium.
Interventions
DEVICEslit lamp
1. Presence of white grayish exfoliation material on the anterior lens capsule and / or the pupillary margin. 2. Poor pupillary dilatation due to atrophy of the dilator pupillae muscle. 3. The presence of pseudoexfoliative material (PXF)in cilliary processes and zonules. 4. presence of PXF material scattered on corneal endothelium. 5. Flecks of the exfoliative material on the anterior chamber which leads to glaucoma.
Sponsors
Assiut University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Phakic patients presenting to Ophthalmology outpatient clinic Of Assiut University Hospital.
Exclusion criteria
* Patients with previous intraocular surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the percentage of diabetic patients with pseudo-exfoliation syndrome | 10 minutes | slit lamp examination of all diabetic patients to get the percentage of those with pseudo-exfoliation syndrome |
Outcome results
None listed