Pancreatitis, Acute
Conditions
Brief summary
changes in high sensitive C reactive protien with different treatment modalities in acute pancreatitis
Interventions
DIAGNOSTIC_TESTHigh sesitive C reactive protien
High sesitive C reactive protien will be evaluated at admission time and after 36 hours
Sponsors
Assiut University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age\>=18 years * Diagnosis of acute pancreatitis confirmed by at least 2 of the following: 1. Typical epigastric abdominal pain 2. Elevation amylase/lipase \>3 times upper limit normal and/or 3. Confirmatory findings on cross-sectional imaging 4. Enrollment within 8 hours of presentation
Exclusion criteria
* Class II or greater NYHA heart failure * Oxygen dependent COPD * Chronic kidney disease\>stage 2 * Existing necrosis on abdominal CT * Organ dysfunction prior to enrollment * Sepsis * Acute respiratory distress syndrome * Malignancy not in remission for at least 5 years * Active drug use * Known allergy to dexamethasone * Altered mental status * Insulin-requiring diabetes * Abdominal surgery within 60days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| High sesitive C reactive protien | 72hours | Level of High sesitive C reactive protien expected to be changed with different lines of treatment and will be compaered |
| Serum Amylase | 72hours | Level of Serum Amylase expected to be changed with different lines of treatment and will be compaered |
| Serum Lipase | 72hours | Level of Serum Lipase expected to be changed with different lines of treatment and will be compaered |
Countries
Egypt
Contacts
Primary Contactmahmoud Abd Elhamed, principal participant
Outcome results
None listed