Coronary Artery Disease
Conditions
Brief summary
This study evaluates cardiac biomarkers and their association to coronary artery disease in marathon runners.
Detailed description
The MaraCat study is an observational prospective study evaluating the association between cardiac biomarkers and coronary artery disease in 43 runners participating in the 2018 Paavo Nurmi Marathon. The study participants were recruited according to two age criteria - under 35 years and over 44 years of age. Comprehensive laboratory samples were collected immediately after the run, while the control workup was done in a separate visit with no significant physical excercise in the preceding two weeks. In the under 35 years -group, the control workup included an echocardiography, ecg and blood samples. In the over 44 years group, the control studies included coronary CT, echocardiography, ecg and laboratory tests.
Interventions
None listed
Sponsors
University of Turku
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
35 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* Age under 35 years or over 44 years * Participant of Paavo Nurmi Marathon 2018 * Informed consent signed
Exclusion criteria
* No informed consent * existing coronary artery disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiac Troponin-T level after marathon | 0-30minutes after finishing the Paavo Nurmi Marathon | Cardiac troponin-T levels (ng/L), \[electrochemiluminescence (ECLIA) method\] |
| Association Cardiac troponin-T level and coronary CT findings | Cardiac Troponin-T 0-30 minutes after finishing the Paavo Nurmi Marathon. Control Troponin-T levels and coronary CT angiography at control visit (>30days after marathon). | Cardiac troponin-T levels (ng/L), \[electrochemiluminescence (ECLIA) method\] |
Countries
Finland
Outcome results
None listed