Cystic Fibrosis
Conditions
Keywords
cystic fibrosis, quality of life, posture
Brief summary
Cystic fibrosis is a genetic disease that affects some organs of the human body. Among them, the lungs tend to be the most affected due to the accumulation of mucus in the airways, which in addition to avoiding the passage of air, favors pulmonary infections. With the evolution of the condition, secondary complications arise, such as postural changes, decreased respiratory muscle strength, decreased functional capacity and, consequently, quality of life. Therefore, respiratory muscle training may be an intervention that improves the respiratory condition of these individuals, allowing an improvement in the quality of life and may delay the evolution of respiratory symptoms. Thus, this study aims to investigate a home protocol of respiratory muscle training on respiratory muscle strength, lung function, quality of life, posture and functional capacity in adolescents and adults with cystic fibrosis. The researchers believe that the training can cause an improvement in the studied variables, and can be inserted in the usual treatment of these patients.
Interventions
DEVICEInspiratory muscle training
This group will initiate inspiratory muscle training with 40% of the MIP load and each week will have a load increase of 10% of the initial MIP up to 4 weeks of training
Sponsors
Universidade Federal do Rio Grande do Norte
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
14 Years to 25 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of cystic fibrosis, confirmed by the sweat test; * 14 - 25 years; * Clinical stability; * Absence of bacterial colonization for 4 weeks; * Both sexes;
Exclusion criteria
* Inability to perform the protocol established by the study; * Present any intercurrence during data collection; * Being unable to understand and / or perform procedures. * Colonization during study participation; * Patient hospitalization due to worsening of the clinical picture.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline Health-related quality of life at 4 weeks | Baseline and after 4 weeks of training | Health-related quality of life questionnaire (HRQoL) |
| Change from baseline Posture at 4 weeks | Baseline and after 4 weeks of training | Inclinometer Danoplus® |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline Respiratory muscle strength at 4 weeks | Baseline and after 4 weeks of training | MVD300® |
| Change from baseline Pulmonary function at 4 weeks | Baseline and after 4 weeks of training | Spirometry test using Koko® device |
| Change from baseline Functional capacity at 4 weeks | Baseline and after 4 weeks of training | three-minute step test |
Countries
Brazil
Outcome results
None listed