PreDiabetes
Conditions
Brief summary
To study the effects of Hesperidin and flaxseed supplement in patients with prediabetes, 50 patients will be randomly allocated to control group or 2 capsules Hesperidin and 30 gram flaxseed for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, lipid profiles, blood pressure, blood sugar, inflammatory and anthropometric factors will be assessed and compared between groups.
Interventions
DIETARY_SUPPLEMENThesperidin and flaxseed
2 capsuls hesperidin and 30 g flaxseed
OTHERcontrol
no supplementation
Sponsors
National Nutrition and Food Technology Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Age of 18 to 70 years prediabetes: impaired fasting glucose (\>100 mg/dL) and/or HbA1C 5.7% to 6.5%, and overweight or obese with body mass index range of 25 to 40 kg/m2
Exclusion criteria
* pregnancy or lactation * A history of Cardiovascular disease, Pulmonary disease, Renal disease & Celiac disease; Cirrhosis * Following program to lose weight in recent 3 mo
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| prediabetes | 12 weeks | number of participants with normal plasma glucose |
Countries
Iran
Outcome results
None listed