Cardiac Surgery, Endocrine System Diseases, Psychology, Social, Quality of Life
Conditions
Brief summary
In this prospective study the investigators want to measure the serum level changes of the thyroid hormones (thyroid-stimulating hormone, reverse triiodothyronine, serum free T4), brain natriuretic peptide (BNP), testosterone and sexual hormone binding protein (SHBG) in adults undergoing cardiac surgery and search for correlations different psychosocial factors and analyze the influence on the survival and the length of ICU/hospital stay.
Detailed description
In this study the investigators want to analyze routinely collected data of patients who underwent any kind of elective cardiac surgery in our university cardiovascular centre between 07.01.2018 and 30.06.2020. The database contains descriptive parameters, history of past illnesses, recent medication. The investigators record the type of surgery, the list of contributory physicians, the length of the surgery and the data of the anaesthesiological report. After the surgery the researchers want to record the postoperative parameters on the ICU ( infusion - fluid balance, blood transfusion, bleeding, main hemodynamic parameters, length of mechanical ventilation,main parameters of arterial blood gas analysis). Moreover th investigators want to collect psychosocial tests (Beck Depression Inventory, State Anxiety Scale, Trait Anxiety Scale and EQ-5D for the measurement of quality of life) to get more information from the postoperative condition of the patients.
Interventions
None listed
Sponsors
Semmelweis University Heart and Vascular Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* elective cardiac surgery
Exclusion criteria
* lack of consent * pregnancy * acute surgery * exposition with iodin-containing contrast material
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Length of hospital and intensive care unit stay | Participants will be followed for the duration of hospital stay, an expected average of 2 weeks. | The correlation of the measured pre and postoperative endocrine profile and the length of intensive care unit stay |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between preoperative EQ-5D inventory and the length of total hospital stay | Participants will be followed for the duration of hospital stay, an expected average of 12 weeks. | Correlation between the preoperative quality of life state and the hospital stay |
| The composite of in-hospital death from any cause. | Participants will be followed for the duration of hospital stay, an expected average of 12 weeks. | Any cause of death in current group |
| Correlation between preoperative Beck Depression Inventory and the length of hospital stay | Participants will be followed for the duration of hospital stay, an expected average of 12 weeks. | The effect of psychological state of the length of hospital stay |
| Correlation between preoperative State Anxiety Scale and the length of hospital stay | Participants will be followed for the duration of hospital stay, an expected average of 12 weeks. | The effect of psychological state of the length of hospital stay |
| Correlation between preoperative Trait Anxiety Scale and the length of hospital stay | Participants will be followed for the duration of hospital stay, an expected average of 12 weeks. | The effect of psychological state of the length of hospital stay |
Countries
Hungary
Outcome results
None listed