Acute Kidney Injury, Early Diagnosis, Outcomes
Conditions
Brief summary
Acute kidney injury (AKI) is a common disease, but diagnosis is usually delayed or missed in hospitalized patients. The automated electronic alert for AKI may help to improve the outcomes of these patients through identifying all cases of AKI early. Therefore, the investigators conduct a randomly controlled study to test whether automated electronic alert for AKI could improve the outcomes of hospitalized patients.
Detailed description
Acute kidney injury (AKI) is a common disease, but diagnosis is usually delayed or missed in hospitalized patients. The automated electronic alert for AKI may help to improve the outcomes of these patients through identifying all cases of AKI early. Therefore, the investigators conduct a randomly controlled study to test whether automated electronic alert for AKI could improve the outcomes of hospitalized patients. The patients were randomly divided into two groups: Usual care : patients will receive standard clinical care by the primary physicians AKI alert : an AKI alert will be sent to the doctor in charge. The team of kidney experts would give a suggestion if the doctor in charge need a renal consultation.
Interventions
DEVICEAKI alert
An AKI alert will send to the doctor in charge. The team of nephrologists would give suggestions if the doctor in charge need a renal consultation.
OTHERUsual care
Patients will receive standard clinical care by the doctor in charge.
Sponsors
The First Affiliated Hospital with Nanjing Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
All study investigators and participants were blinded to patients randomization status.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Hospitalized adult patients with an Alert for AKI(based on KDIGO guidelines)
Exclusion criteria
* Patients already having eGFR\<15ml/min/1.73m2 or receiving renal replacement therapy for AKI at the time of alert. * Patients already having a AKI before admission.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Estimated glomerular filtration rate changed within 7 days | within 7 days diagnosed with AKI | Medical record |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 30-day mortality | within 30 days diagnosed with AKI | Medical record |
| 1-year mortality | within 1 year diagnosed with AKI | telephone follow-up |
| receiving renal replacement therapy at seventh day | 7 days | Medical record |
| receiving renal replacement therapy at 30th day | 30 days | telephone follow-up |
| receiving renal replacement therapy at 1 year | 1 year | telephone follow-up |
| seven-day mortality | within 7 days diagnosed with AKI | Medical record |
| the rate of stage 3 AKI | within 7 days diagnosed with AKI | Medical record |
| the rate of AKI recovery at 90 day | 90 days | telephone follow-up |
| the rate of timely-recognition of AKI | 3 days | Medical record |
| the interventions for AKI | within 7 days diagnosed with AKI | Medical record |
| Follow-up rate after discharge | 1 year | telephone follow-up |
| the rate of stage 2 AKI | within 7 days diagnosed with AKI | Medical record |
Countries
China
Outcome results
None listed