Vitamin D Deficiency
Conditions
Keywords
vitamin D3, vitamin D deficiency, leptin, A1C, omega-3 fatty acid
Brief summary
The Combined effect of Vitamin D3 and Omega-3 supplements on serum leptin and Glycated hemoglobin (Hb A1C) levels in Jordanian people with vitamin D deficiency.
Detailed description
Nothing is published in the literature about effect of vitamin D3 (VD3) and omega-3 fatty acids (omega-3FA) on serum leptin and glycated hemoglobin ( HbA1C) This study will be conducted to investigate effect of VD3 and omega-3FA alone and with each other on serum leptin and Glycated hemoglobin (Hb A1C) levels in Jordanian people with vitamin D deficiency. This randomized, controlled clinical trial will be designed to test effects of 50,000 IU VD3 weekly and 1000 mg omega-3FA daily for eight weeks, separately and with each other, on on serum leptin and Glycated hemoglobin (Hb A1C) levels .
Interventions
DIETARY_SUPPLEMENTVD3 group
VD3 50000 IU/ week for 8 weeks
DIETARY_SUPPLEMENTomega 3 FA group
omega 3 FA group 300 mg once daily for 8 weeks
DIETARY_SUPPLEMENTVD3 and omega- 3FA group
50000 IU VD3/week for 8 weeks and 300 mg of omega- 3 FA once daily for 8 weeks
OTHERcontrol group
no intervention was given
Sponsors
Applied Science Private University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
25 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* jordanian people aged 25-55 * medical diagnosis of vitamin D deficiency ( VD \<25 ng/ ml)
Exclusion criteria
* Blood disorders including * thalassemia * sickle cell disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VD 3 | 8 weeks | Serum level of 25-hydroxyvitamin D |
| leptin | 8 weeks | serum level of leptin |
| HbA1C | 8 weeks | plasma concentration of HbA1C |
Countries
Jordan
Outcome results
None listed