Metabolic Syndrome
Conditions
Brief summary
To study the effects of Hesperidin, flaxseed and both together in patients with metabolic syndrome, 100 patients will be randomly allocated to one of following four groups: control group, hesperidin group (2 capsules Hesperidin), flaxseed group (30 gram flaxseed) or flaxseed-hesperidin group (2 capsules Hesperidin and 30 gram flaxseed) for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, metabolic factors will be assessed and compared between groups.
Interventions
DIETARY_SUPPLEMENThesperidin
1000 mg hesperidin as two capsules
DIETARY_SUPPLEMENThesperidin and flaxseed
1000 mg hesperidin as two capsules and 30 grams flaxseed
DIETARY_SUPPLEMENTflaxseed
30 grams flaxseed
OTHERcontrol
no supplementation
Sponsors
National Nutrition and Food Technology Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Age of 18 to 70 years * having 3 of 5 of high blood sugar, hypertension, high TG, high waist circumference, low HD
Exclusion criteria
* pregnancy or lactation * history of Cardiovascular disease, Pulmonary disease, Renal disease & Celiac disease; Cirrhosis * Following a program to lose weight in recent 3 mo
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Metabolic syndrome: Number of participants with treated metabolic syndrome | 12 weeks | Number of participants with treated metabolic syndrome |
Countries
Iran
Contacts
Primary Contactazita Hekmatdoost, MD.PhD
Outcome results
None listed