Cardiovascular Risk Factor
Conditions
Brief summary
We compared the effects of 8 weeks of aerobic exercise only, resistance exercise only, or a combination of both on blood pressure in overweight or obese middle-aged adults with elevated blood pressure. Participants engaged in supervised exercise sessions 3 times per week for 60 minutes each session. Outcomes were assessed at baseline and after the 8-week intervention. Extra-intervention physical activity and diet were also assessed.
Interventions
BEHAVIORALAerobic Exercise
180 minutes of moderate-vigorous intensity aerobic exercise per week
BEHAVIORALResistance Exercise
180 minutes of resistance exercise per week
BEHAVIORALCombined aerobic and resistance exercise
180 minutes of exercise per week with 90 minutes per week coming from moderate-vigorous intensity aerobic exercise and 90 minutes per week coming from resistance exercise
Sponsors
Iowa State University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Outcomes Assessor)
Masking description
The outcomes assessor was blinded to treatment group allocation.
Intervention model description
randomized controlled trial
Eligibility
Sex/Gender
ALL
Age
45 Years to 74 Years
Healthy volunteers
Yes
Inclusion criteria
* Systolic/diastolic blood pressure of 120-159/80-99 mm Hg * Non-smoking * Overweight or obese, with a body mass index of 25-40 kg/m2 * Inactive--not meeting the aerobic or resistance physical activity guidelines, which means engaging in less than 150 minutes/wk of moderate intensity aerobic exercise and less than 2 days per week of resistance training over the past 3 months.
Exclusion criteria
* Unstable coronary heart disease or decompensated heart failure * Severe pulmonary hypertension or aortic stenosis * Acute myocarditis, endocarditis, pericarditis, or aortic dissection * Other medical condition that is life-threatening or that can interfere or be aggravated by the exercise training such as cancer, uncontrolled diabetes, severe pain or mobility limitations. * Premenopausal women or postmenopausal women taking hormonal replacement therapy * Pregnant women or anticipated pregnancy via IVF or other medical procedures during the course of the intervention
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in resting blood pressure | Immediately before and after the 8 week intervention | resting systolic and diastolic blood pressure |
Outcome results
None listed