Knee Osteoarthritis, Nerve Block, Total Knee Arthroplasty
Conditions
Brief summary
This study compares analgesic effect between two techniques of adductor canal nerve block after total knee arthroplasty. The first group of the patients will receive intraoperative adductor canal nerve block; and the other group post operative ultrasound guided adductor canal nerve block. Investigators will measure postoperative opioid consumption, pain management and rehabilitation goals.
Detailed description
Total knee arthroplasty (TKA) is a successful alternative to treat late stage knee osteoarthritis (OA). Pain management has been one of the main focuses of postoperative care. Most surgeons prefer a comprehensive multimodal approach including preoperative pharmacological treatment, intraoperative infiltration with complex drug mixes and postoperative peripheral nerve block. The most common postoperative nerve block alternative is the proximal femoral nerve block (FNB) which has shown improvements on postoperative pain measured by reduced opioid consumption and decreased pain at rest. Its main detractors argue that the motor nerve block effect is deleterious to early ambulation and have promoted adductor canal nerve blocks (ACB). Described by Lund et al in 2011, ACB block main femoral pain sensory contributors to the knee (articular branches of obturator nerve, vastus medialis branch and saphenous nerve) but is more distal to most motor branches to the quadriceps allowing near to normal quadriceps strength. Standard ACB block is performed under ultrasound guidance after surgery completion, still in the operating room (OR). Recent literature has shown the anatomic feasibility of intraoperative ACB via blunt suprapatellar dissection in standard medial parapatellar TKA approaches. The study seeks to determine the effectiveness of standard ultrasound guidance ACB compared with intraoperative ACB.
Interventions
One shot adductor canal nerve block with 20ml of bupivacaine 0.25% through surgical incision
One shot adductor canal nerve block with 20ml of bupivacaine 0.25% mid-thigh
One shot adductor canal nerve infusion with 20ml of saline solution through surgical incision
One shot adductor canal nerve infusion with 20ml of saline solution mid-thigh
Sponsors
Study design
Masking description
Total blind (patient, physicians, outcome assessors and statistician) Closed envelope by independent randomizer is given to physician assistant. The assistant prepares randomly allocated placebo or local anesthetic. Group is coded so that statistician is also blind
Intervention model description
Two arm, randomly assigned
Eligibility
Inclusion criteria
* Primary total knee arthroplasty * Unilateral * American Society of Anesthesiologists (ASA) score I, II or III * Accepts spinal anesthesia
Exclusion criteria
* General anesthesia * Chronic kidney disease * Drug or alcohol abuse * Chronic opioid use * Allergic to bupivacaine or similar
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 24 hour opioid consumption | First 24 hours after surgery | Opioid consumption by patient controlled analgesia (PCA) and any other oral or IV analgesics |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 24 patient reported pain | First 24 hours after surgery | Patient reported pain scale using visual analog scale (VAS) every 6 hours after surgery (0 hours, 6 hours, 12 hours, 18 hours and 24 hours) |
| Time up and go Test | 24 hours after surgery | Standardised test to determine patients ability to walk 24 hours after surgery |
| Time to Discharge | 7 days | Time between surgery and patient in conditions for discharge: no IV requirements, basic walking capability and VAS pain score equal or below 3 |
| Range of motion | 24 hours after surgery | Active and passive knee range of motion |
Countries
Chile