Sarcopenia and Orthostatic Hypotension

The Relationship Between Sarcopenia and Orthostatic Hypotension

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03732716

Enrollment

100

Registered

2018-11-07

Start date

2018-09-10

Completion date

2018-12-31

Last updated

2018-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthostatic Hypotension, Sarcopenia

Keywords

blood pressure, elderly, sarcopenia, fall

Brief summary

Elderly patients generally have a tendency for having sarcopenia which refers to muscle loss that may be related to many factors. These patients also have a tendency to falls and injuries. Whether elderly sarcopenic patients have abrupt blood pressure drops upon standing remains unknown. Therefore, in this study, we sought to determine the incidence of orthostatic hypotension in sarcopenic elderly patients and compare it with elderly patients with no sarcopenia.

Interventions

DIAGNOSTIC_TESTblood pressure measurement

Intervention: Each patient's supine and standing blood pressure measurements will be recorded

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

75 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients 75 years or older

Exclusion criteria

* Pace-maker * End stage renal insufficiency * End stage malignancy * Dehydration * Severe anemia ( Hgb \< 8 gr/dl) * Acute infection * Marked edema * Neurodegenerative disease

Design outcomes

Primary

Measure	Time frame	Description
Change in blood pressure	0-3 minutes	All blood pressure measurements will be performed in the morning after an eight-hour fasting. After 5-minute rest, the first blood pressure measurement will be taken when the patients are supine. Later, three more consecutive measurements will be recorded when the patients stand up each being one-minute apart. All measurements will be performed using a fully automated sphygmomanometer that is attached with the correctly sized cuff matching to the patients' upper arm circumference. OH is defined as a decrease in systolic blood pressure of 20 mm Hg or a decrease in diastolic blood pressure of 10 mm Hg within 3 minutes of standing. The accompanying symptoms such as dizziness, unable to maintain balance, blurred vision will also be recorded.

Countries

Turkey (Türkiye)

Contacts

Primary ContactKudret Keskin, MD

keskinkudret@yahoo.com0212 3735000

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026