Clinico-epidemiological Characteristics of Corrosive Patients Presenting at Assiut Governorate
Conditions
Brief summary
Esophageal stricture is one of the most common sequelae of caustic injury. Up to 70% of patients with grade IIB and more than 90% of patients with grade III injury are likely to develop esophageal stricture. Stricture formation can be prevented by suppressing fibrosis and scar formation therefore; many agents are explored for treatment on various models in this subject.
Detailed description
In spite of the multiple efforts to educate the public, Caustic ingestion maintains its place as an important public health issue due to the availability of caustic agents and the loose regulatory control on its production. All the cases will be evaluated by detailed history and thorough physical examination and necessary investigations. Patient's sheet will include; name, age, sex, occupation, residence, type of administrated substance, route and mode of exposure, symptoms and sighs (pain , vomiting , diarrhea) and any received treatment.
Interventions
BEHAVIORALdevelopment of complications or not
assessment of development of complications
Sponsors
Assiut University
Study design
Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Months to 50 Years
Healthy volunteers
No
Inclusion criteria
-1- All the cases with the primary diagnosis of acute caustic injury will be included in the study. 2- Willing and able to comply with the study procedures and provide written informed consent to participate in the study.
Exclusion criteria
* 1- Caustic substance ingested patient with any chronic disease. 2- Patients with history of congenital esophageal stricture. 3- Unable to provide informed consent. 4- Unlikely to return at 8 weeks. 5- Ingestion of substances other than corrosive (co-ingestion).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| fate of cases | 6 months | development of esophageal stricture or not |
Outcome results
None listed