Epidemiology and Long Term Outcome of Critically Ill Patients Requiring Renal Replacement Therapy in Southeast Asia and India (InSEA-RRT Registry)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03727997

Acronym

InSEA-RRT

Enrollment

2315

Registered

2018-11-01

Start date

2019-04-01

Completion date

2024-12-01

Last updated

2025-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Keywords

Acute kidney injury, Renal replacement therapy, Intensive Care Unit

Brief summary

Acute kidney injury is associated with increased short-term and long-term morbidity and mortality. Long-term data is lacking in low to middle-income countries. Our study aims to follow the acute kidney injury patients stage 3 in intensive care units for 2 years to observe mortality and associated factors.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* AKI stage 3 * At least 18 years old

Exclusion criteria

* ESRD patients (eGFR \< 15 mL/min/1.73 m2)

Design outcomes

Primary

Measure	Time frame
2-year mortality	2-year

Secondary

Measure	Time frame	Description
Hospital mortality	28-day	—
RRT rate	28-day	—
Renal recovery	28-day	Number of Participants with who survive. Number of Participants with dialysis independence and creatinine \<1.5 mg/dL
2-year major adverse kidney events	2-year	Number of Participants with 25% or greater decline in eGFR. Number of participants who receive new renal replacement therapy (RRT).

Countries

Thailand

Outcome results