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Machine Learning-Based Risk Profile Classification of Patients Undergoing Elective Heart Valve Surgery

Machine Learning-Based Risk Profile Classification of Patients Undergoing Elective Heart Valve Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03724123
Enrollment
2229
Registered
2018-10-30
Start date
2008-01-01
Completion date
2014-12-31
Last updated
2018-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Valve Diseases, Surgery--Complications

Keywords

random forests, heart valve surgery, support vector machines, artificial neural networks

Brief summary

Machine learning methods potentially provide a highly accurate and detailed assessment of expected individual patient risk before elective cardiac surgery. Correct anticipation of this risk allows for improved counseling of patients and avoidance of possible complications. The investigators therefore investigate the benefit of modern machine learning methods in personalized risk prediction in patients undergoing elective heart valve surgery.

Detailed description

The investigators performe a monocentric retrospective study in patients who underwent elective heart valve surgery between January 1, 2008, and December 31, 2014 at our center. The investigators use random forests, artificial neural networks, and support vector machines to predict the 30-days mortality from a subset of demographic and preoperative parameters. Exclusion criteria were re-operation of the same patient, patients that needed anterograde cerebral perfusion due to aortic arch surgery, and patients with grown up congenital heart disease.

Interventions

None listed

Sponsors

Institute of Bioinformatics, JKU Linz
CollaboratorUNKNOWN
Kepler University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

\* Patients who underwent heart valve surgery of any kind between 2008-01-01 and 2014-12-31 were included.

Exclusion criteria

* re-operation of the same patient * patients that needed anterograde cerebral perfusion due to aortic arch surgery * patients with grown-up congenital heart disease

Design outcomes

Primary

MeasureTime frameDescription
Area under the curve for different prediction modelsPatients will included from 01.01.2008 - 31.12.2014Three different predictions models will be used.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 15, 2026