Healthy
Conditions
Keywords
amygdala, mirror neuron system, brain network
Brief summary
Identify if the mirror neuron system, or other networks, can compensate for amygdala dysfunction, using behavior and structural/functional MRI.
Detailed description
In the present study, investigators aim to investigate amygdala dysfunction & potential compensation in individuals with high and low traits (e.g. Autism, Anxiety, Depression traits, Alexithymia), high and low stress or protective factors in the environment (social network, early life stress) and different molecular genetic make-up. On the neural level, functional and structural connectivity as well as task-related BOLD activation will be assessed.
Interventions
BEHAVIORALscreen high and low triat subjects
use a range of questionniares to screen screen high and low triat subjects (eg. Autism, Anxiety, Depression traits and social network size)
Sponsors
University of Electronic Science and Technology of China
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
17 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy subjects
Exclusion criteria
* history of head injury * claustrophobia; * medical or psychiatric illness * female subjects were pregnant or taking oral contraceptives. * taking any form of medication and drunk any caffeine-containing beverages on the day of the experiment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| brain activity and connectivity during social and cognitive tasks | 2 hours | brain activity and connectivity was measured by the fMRI scanner |
Countries
China
Contacts
Primary ContactKeith Kendrick, Dr.
Outcome results
None listed