Variable Resistance Training in Patients With Osteoarthrosis of the Knee

Variable Resistance Training Versus Conventional Rubber Band Training: Effects on Functional Capacity and Strength in Patients With Osteoarthrosis of the Knee

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03722277

Enrollment

Registered

2018-10-26

Start date

2018-10-22

Completion date

2020-09-01

Last updated

2018-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Resistance Training

Brief summary

This is a randomized controlled trial investigating the effect of variable load training in patients with knee osteoarthrosis. The intervention will consist of resistance training with variable load in knee extension- and flexion. The control group will receive conventional strength training with rubber band. Outcome measures will be the Knee Osteoarthrosis Outcome Score, functional capacity measured in a sit to stand test, 30m. pace walk and a 9 step stair climb test. Additionally isometric strength in knee flexion- and extension will be measured.

Interventions

OTHERVariable load training

Based on symptoms/strength measured in an isometric maximum strength test at five different angles of knee flexion- and extension, participants will be training with variable load during both concentric and excentric phase of the dynamic movement. Initially participants will start at 40% of symptom limited isometric strength, this will increase to 50% during the training period.

OTHERConventional strength training

Conventional strength training with rubber bands in knee flexion- and extension, additionally hip abduction- and adduction.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

50 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Knee pain and minimum three of the following * \>50 years * morning stiffness \< 30 min * crepitation * bone tenderness * bone osteophytes * absence of inflammation

Exclusion criteria

* Other causes of symptoms to the knee

Design outcomes

Primary

Measure	Time frame	Description
Change in self reported knee function	At baseline and 10 weeks follow up	Knee Osteoarthrosis Outcome Score (100-0, 100 indicating no symptoms and 0 indicating extreme symptoms)

Secondary

Measure	Time frame	Description
Change in functional capacity	At baseline and 10 weeks follow up	Sit to stand test
Change in isometric strength	At baseline and 10 weeks follow up	Isometric strength in knee flexion- and extension

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026