Catheter Related Blood Stream Infections
Conditions
Keywords
Vancomycin, Therapeutic drug monitoring, Catheter related blood stream infections
Brief summary
The goal of this study is to verify whether extensive flushing of the port catheter in patients with catheter related blood stream infection will lead to correct vancomycin trough levels, taken via the port catheter and compared with simultaneously taken peripheral samples.
Detailed description
In this study, extensive flushing of the port catheter prior to blood sampling to determine vancomycin trough levels, will be compared with normal flushing. To ascertain correctness of the trough levels taken via the central catheter, sampling will occur through a peripheral catheter simultaneously. Flushing will be done with sodium chloride 0.9 % solution.
Interventions
PROCEDUREExtensive flushing of the port catheter
The port catheter will be flushed extensively with sodium chloride 0.9% before blood sampling. Blood sampling will occur through the central catheter and peripherally simultaneously.
Sponsors
Universitaire Ziekenhuizen KU Leuven
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* Pediatric patients with a port catheter * Treated with systemic vancomycin and/or vancomycin lock
Exclusion criteria
* Age \> 18 years * Active downgrading of care
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vancomycin trough levels via port catheter and peripheral vein | At steady state i.e. approximately 36 hours after initation of the treatment or a change in dose | Vancomycin trough levels will be determined, both on peripheral blood and blood taken via the port catheter and will be compared. |
Countries
Belgium
Outcome results
None listed