Decayed Tooth, Fractured Tooth, Unsatisfactory Restoration of Tooth
Conditions
Keywords
Crown, Ceramic, CAD/CAM
Brief summary
This investigation will be a clinical trial to study the performance of a new resin-based ceramic material for crowns. The material has been approved by the FDA for patient treatment. A computer technique will be used to fabricate the crowns in a single appointment without the need for a temporary crown or second appointment. The purpose of the study is to measure how well the high strength crowns function over an extended period of time.
Detailed description
The study will be composed of 50 crowns placed in adult patients that have been identified as requiring at least one crown on a posterior tooth. A maximum of two crowns per patient will be completed. All the crowns will be made from the same resilient ceramic CAD/CAM block(Tetric CAD/Ivoclar Vivadent). The crowns are placed using an adhesive bonding process including a total etch process with a universal adhesive (Adhese by Ivoclar Vivadent) and dual-cured resin cement (Variolink Esthetic by Ivoclar Vivadent). The crowns are planned to be evaluated at 6 months, 1 year, 2 years, 3 years, and if funding permits, 4 years, and 5 years. At each appointment, an examination of the crown will be completed as well as clinical photographs, an intraoral digital scan, and impression of the crown.
Interventions
DEVICETetric CAD
Resilient ceramic crowns (Tetric CAD by Ivoclar Vivadent) are placed using an adhesive bonding process including a total etch process with a universal adhesive (Adhese by Ivoclar Vivadent) and dual cured resin cement (Variolink Esthetic by Ivoclar Vivadent).
Sponsors
University of Michigan
Ivoclar Vivadent AG
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* must have at least one carious lesion or defective restoration or fractured tooth in a molar or premolar * reason for restoration should extend more than one-half the intercuspal width of the tooth requiring a full crown restoration * Teeth to be vital and asymptomatic prior to treatment * No more than two restorations will be placed per patient. If a patient presents with more than two acceptable teeth for the study, molar teeth will be included prior to premolar teeth.
Exclusion criteria
* Devital or sensitive teeth * Teeth with prior endodontic treatment of any kind * Teeth with a history of direct or indirect pulp capping procedures * Patients with significant untreated dental disease to include periodontitis and rampant caries * Pregnant or lactating women * Patients with a history of allergies to any of the materials to be used in the study * Patients unable to return for the recall appointments
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Crown Failure | from delivery of the crown up to 5 years | Crown failure includes fracture of the crown or loss of the crown requiring placement of a new crown at any time between delivery and five years. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Crown Loss of Retention | from delivery of the crown up to 5 years | Loss of retention is measured as detachment of the crown from the tooth without fracture of the crown requiring recementation of the crown. |
| Tooth Sensitivity | from delivery of the crown up to 5 years | Tooth Sensitivity is evaluated as either "0" if the subject reports that there is NO sensitivity for the tooth with the study crown, or "1" if the subject reports that there IS tooth sensitivity to hot/cold or biting pressure. The better outcome is to have NO tooth sensitivity. The number of teeth with tooth sensitivity are listed below. |
| Margin Staining | from delivery of the crown up to 5 years | Margin Staining is evaluated as either "0" if there is NO staining at the crown margin where it meets the tooth, or "1" if there IS staining at the crown margin where it meets the tooth. The better outcome is to have NO margin staining. The number of teeth with margin staining are listed below. |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORDennis Fasbinder, DDS
University of Michigan
Participant flow
Recruitment details
The patient population was selected from current patients under clinical treatment at the University of Michigan Dental Clinics between October 2018 and April 2019.
Baseline characteristics
| Characteristic | — |
|---|---|
| Sex: Female, Male Female | 32 Participants |
| Sex: Female, Male Male | 9 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 41 |
| other Total, other adverse events | 0 / 41 |
| serious Total, serious adverse events | 0 / 41 |
Outcome results
None listed