Critically Ill, Hemodynamic Instability, Intraabdominal Hypertension
Conditions
Keywords
Critically ill patients, intraabdominal pressure, hemodynamics, positive end-expiratory pressure
Brief summary
In this study, it was aimed to compare the effects of three different PEEP levels (0-4, 5-8, 9-12 cmH2O) on intraabdominal pressure and hemodynamic parameters of patients in intensive care unit.
Detailed description
Patients between 18-80 years old whom were mechanically ventilated without any spontaneous respiratory efforts on supine position were included into the study. Bladder pressure measurement as a practical and frequently preferred method was used in order to measure intra-abdominal pressure. 100 ml isotonic fluid was given during the measurement. Level of symphysis pubis was chosen for zeroing the pressure transducer to measure the intra-abdominal pressure. Three patient groups, each containing 22 cases, totally 66 patients were planned in this study. All patients were mechanically ventilated with various PEEP levels. The patients with 0-4 cmH2O PEEP levels were named Group 4; the patients with 5-8 cmH2O PEEP levels were named Group 8; the patients with 9-12 cmH2O PEEP levels were named Group 12. The levels of patients' PEEP levels were arranged by the responsible intensive care physician regarding to the patients' clinic. Intraabdominal, central venous, arterial blood pressures, pulse rates, peripheric oxygen saturation, body temperature, instant fluid balances and amounts of urine (in ml/kg/hour unit) of the patients were measured on the 0. 6. 12. 18. and 24. hours and recorded.
Interventions
DIAGNOSTIC_TESTIntraabdominal Pressure Measurement
In this method, a sterile set system (AbViser- Wolfe Tory Medical, Saik Lake City, Utah, USA) was used in normal conditions. Measurements will be made in 20 ml saline was given, Pressure transducer was used as a reset point pubic symphysis and intra-abdominal pressure was measured.
Sponsors
Yuzuncu Yil University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Intervention model description
Intraabdominal pressure of the patients were measured on the 0. 6. 12. 18. and 24. hours and recorded.
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* age between 18-80, * connected to mechanical ventilator in intensive care, * had not undergone surgery of the abdomen, * patients followed at the same PEEP levels for at least 24 hours
Exclusion criteria
* The consent for the study, * initial intrabdominal pressure level is over 12 cmH2O, * undergoing abdominal surgery or bladder surgery, * neurogenic bladder, * morbid obesity, * Chronic Obstructive Pulmonary Disease Patients were excluded from the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measure intraabdominal pressure | 1 month | Intraabdominal Pressure Measurement In this method, a sterile set system (AbViser- Wolfe Tory Medical, Saik Lake City, Utah, USA) was used in normal conditions. Measurements will be made in 20 ml saline was given, Pressure transducer was used as a reset point pubic symphysis and intra-abdominal pressure was measured. |
Countries
Turkey (Türkiye)
Outcome results
None listed