Labor Pain
Conditions
Keywords
Labor analgesia, Programmed intermittent epidural bolus
Brief summary
Comparison of three programmed intermittent epidural bolus (PIEB) pump settings for maintenance of labour analgesia.
Detailed description
The optimal PIEB and patient controlled epidural administered (PCEA) bolus settings are still unknown. Therefore, in this study, the investigators aim to compare analgesia outcomes both high and low PIEB flow rate settings.
Interventions
DRUGBupivacaine 0.08% - fentanyl 2mcg
In each arm, bupivacaine and fentanyl are being delivered at different intervals and rates for the maintenance of labor analgesia.
Sponsors
University of British Columbia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
FEMALE
Age
19 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Singleton, vertex presentations at term (37-42 weeks gestational age) * \</= 5cm cervical dilation at the time of epidural anesthesia request * ASA 2-3 patients aged 19 or over who are able to provide informed consent
Exclusion criteria
* Contraindications to neuraxial analgesia or risk factors likely to affect placement or function of the epidural * History of hypersensitivity or idiosyncratic reaction to local anesthetics or opioids * Current or historical evidence of any significant medical conditions * Clinical settings in which continuous epidural infusion may be preferable * Risk factors significantly increasing the need for Cesarean delivery * Anticipated fetal abnormalities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Breakthrough pain | Duration of labor with epidural | Proportion of patients in each group who required a provider administered supplemental bolus for breakthrough pain |
Countries
Canada
Outcome results
None listed