Healthy
Conditions
Brief summary
This study aims to examine the effects of transcranial direct current stimulation at corticobulbar excitability in individuals with different gene polymorphism.
Detailed description
The effects of TDCS on corticobulbar excitability of the brain after inhibitory pre-conditioning will be compared in patients with different BDNF phenotypes
Interventions
DEVICEtdcs
application of optimised parameters of tDCS (anodal stimulation, 1.5 mA, 10 min) over the unconditioned hemisphere reverses the brain and behavioural consequences of inhibitory pre-conditioning
Sponsors
The Catholic University of Korea
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
19 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 19-40 years * Informed consent
Exclusion criteria
* History of epilepsy * Presence of cardiac pacemaker * previous brain surgery * previous swallowing problems * current use of medication which acts on the central nervous system * presence of implanted metal intracranially
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Brain corticobulbar excitability | Immediately after single conditioning the brain | Change of Brain corticobulbar excitability by motor evoked potentials |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Tongue pressure measurement- | Immediate after single conditioning the brain | Change of tongue pressure measurement by Intra oral pressure assessment |
| Electrophysiological responses of swallowing - | Immediate after single conditioning the brain | Change of Electrophysiological responses of swallowing - With the use of a laryngeal transducer, will measure the mylohyoid amplitude |
Countries
South Korea
Outcome results
None listed