Chronic Kidney Diseases
Conditions
Keywords
chronic kidney disease, uremic toxin, prognosis
Brief summary
The aim of this cohort study is: To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.
Detailed description
To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.
Interventions
None listed
Sponsors
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* age ≥18 years old; * clinically diagnosed with chronic kidney disease, according K/DOQI criteria.
Exclusion criteria
* acute kidney injury * history of kidney injury \<3 months * malignancy * pregnancy * incomplete clinical data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| all cause mortality | 5 years |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| comorbidities | 5 years | CVD,mortality,hospitalization |
Countries
China
Contacts
Primary ContactFeng Ding, PhD
Backup ContactWenji Wang, MD
Outcome results
None listed