Effect of an Low Carbon High Fat Diet on Pain- and Quality of Life in Patients With Lipedema

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03710798

Acronym

LIPODIET

Enrollment

Registered

2018-10-18

Start date

2018-10-01

Completion date

2019-01-10

Last updated

2019-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lipedema, Obesity, Morbid

Keywords

Diet, ketogenic, Pain, Quality of Life, Body Composition, Body Fat Distribution

Brief summary

Lipedema is a chronic disease with unproportional, symmetrical fat accumulation in the lower extremities. Patients experience pain in affected areas, and reduced quality of life. Today's treatment is physiotherapy and surgery (liposuction). Recent research shows that ketogenic-diet with low carbohydrate, high fat (LCHF) conant can lead to reduced pain, increased quality of life and change in body composition. Goals: Investigate the effect of LCHF diet on pain, quality of life and body composition.

Interventions

DIETARY_SUPPLEMENTLow carbohydrate high fat diet

Energy balanced low carbohydrate high fat diet during 6 weeks. Then 6-week reintroduction of a healthy normal diet

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Intervention model description

prospective observational study with a diet intervention

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* weight stable over the last three months (+ 2-3 kg) * not currently dieting to loose weight. * willing to meet for weekly follow-ups during the intervention and the reintroduction of a regular diet. * sign an informed consent before entering the study.

Exclusion criteria

* pregnant or breast feeding * history of infectious diseases * medication known to affect obesity * enrolment in any other obesity treatment * have had a bariatric surgery * history of psychological disorders * mentally disabled * not mastering a Scandinavian language * having a malign disease or any disease that leads to dietary advice that is not consistent with intervention advices in the study

Design outcomes

Primary

Measure	Time frame
Lymphedema Quality of Life questionnaire	6 weeks
Pain indicated on a visual analog scale	6 weeks

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026