Non-small Cell Lung Cancer
Conditions
Keywords
Non-small cell lung cancer, gene mutations
Brief summary
A single-center, non-interventional prospective observational study in the NSCLC patients with different driver genes
Detailed description
The trial was designed as a single-center non-interventional prospective observational study to explore clinical treatments of the NSCLC patients with different driver genes, the impact factors of patient survivals, and the relevance of gene types, clinical treatments, and distribution of gene types. The follow-up visits, interactions between the investigators and patients, patient questionnaires/quality of life, and other patient information will be uploaded via mobile APP, and webchat every three months.
Interventions
OTHERPatients with driver genes
Patients with driver genes
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The patients with lung cancer who were performed with next-generation sequencing (NGS) technology from 2015 to 2017; * The patients who were at least 18 years; * The pathologically diagnosed patients with non-small cell lung cancer (NSCLC)
Exclusion criteria
-None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Differences in overall survival rates | 2018-2022 | Differences in overall survival rates of the NSCLC patients with various gene types |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Statuses of clinical treatment regimens | 2018-2022 | Statuses of clinical treatment regimens of the NSCLC patients |
| Relevance of gene types | 2018-2022 | Relevance of gene types and clinical characteristics of the NSCLC patients |
| Relevance of overall survival rates and gene types | 2018-2022 | Relevance of overall survival rates and gene types of the NSCLC patients |
| Interaction impact between gene types and treatment modalities or regimens on disease-free survivals | 2018-2022 | Interaction impact between gene types and treatment modalities or regimens on disease-free survivals |
| Impacts of progression-free survivals | 2018-2022 | Impacts of progression-free survivals on gene types of the NSCLC patients |
| Impact factors of overall survivals | 2018-2022 | Impact factors of overall survivals of the NSCLC patients |
| Impacts of disease-free survivals on gene types | 2018-2022 | Impacts of disease-free survivals on gene types of the NSCLC patients |
Countries
China
Contacts
Primary ContactJianxing HE, MD
Backup ContactWenhua LIANG, Ph.D
Outcome results
None listed