Pain
Conditions
Keywords
Pain, Alzheimers disease
Brief summary
The study investigates pain processing and pain reporting in patients with Alzheimers disease compared to healthy participants. Employing a within-subject design, the study includes patients with Alzheimers disease and healthy participants that are exposed to thermal stimuli. During the test session the facial expressions of the participant are video recorded. By repeating this on separate test days, the involvement of pain relief and pain increase is investigated.
Interventions
BEHAVIORALThermal stimulation
Thermal stimulation
Sponsors
University of Aarhus
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Mild to moderate patients with Alzheimers disease (group 1) * Healthy participants ( group 2)
Exclusion criteria
* Chronic pain conditions * Other medical, psychiatric or neurological disorders * Use of pain-reliving medication 24 hours prior to testing
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Numerical rating scale (NRS) | Participants will be tested on three different days. The numerical rating scale will be applied after each thermal stimulus for each test session. | Acute pain assessed on numerical rating scale from 0 (no pain experience) to 10 (worst pain), examining pain intensity. The participant will provide a number on the scale which reflects their pain intensity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain Assessment in persons with Impaired Cognition (PAIC) | Participants will be video recorded on each of the three test days during testing. | Video recordings will be analyzed with the PAIC scale from 0 (not at all) to 3 (great degree). |
Countries
Denmark
Outcome results
None listed