Single Nucleotide Polymorphisms (SNPs) Associated With Postherpetic Neuralgia

Association Between Some Candidate Single Nucleotide Polymorphisms and Postherpetic Neuralgia

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03708653

Enrollment

181

Registered

2018-10-17

Start date

2018-04-01

Completion date

2019-02-13

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postherpetic Neuralgia

Brief summary

Postherpetic neuralgia (PHN) is a common condition and affecting 5 to 30% of the herpes zoster patients. In some cases, the pain remained refractory after first and second line treatment for herpes zoster. This suggests that there may be genetic variants that make some patients susceptible to PHN. Using saliva samples from herpes zoster patients the investigators are going to analyze the relationship between single nucleotide polymorphisms (SNPs) in genes that are known to be involved in pain and PHN.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age more than 50 years * Clinically defined herpes zoster patients

Exclusion criteria

* Patients not able to provide informed consent

Design outcomes

Primary

Measure	Time frame
correlation between pain SNPs and PHN	At Enrollment

Countries

China

Outcome results