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Tourniquet Reduces Blood Loss in Postpartum Hemorrhage During Hysterectomy for Placenta Accreta

Tourniquet on the Low Segment of the Uterus Reduces Blood Loss in Postpartum Hemorrhage During Hysterectomy for Placenta Accreta: Old But Gold

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03707132
Enrollment
43
Registered
2018-10-16
Start date
2014-10-01
Completion date
2017-09-30
Last updated
2018-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Loss Massive, Placenta Accreta, Post Partum Hemorrhage

Keywords

Tourniquet, low uterus segment, placenta accreta, hysterectomy, massive blood loss management

Brief summary

Monocentric prospective observational study comparing the use of tourniquet in low uterus segement versus standard procedure in hysterectomy owing to placenta accreta

Detailed description

It is a monocentric prospective observational case-control study in the Department C of Gynecology and Obstetrics in the Maternity and Neonatology Center of Tunis during three years from October 2014 to September 2017. All parturient were informed about the possibility of performing a hysterectomy if accretization was clinically confirmed preoperatively. After obtaining written formal consent. all patients who underwent scheduled or emergency cesarean section for placenta accreta were included. Either it was highly suspected or confirmed by obstetrical imaging. MRI was always performed in cases of scheduled cesarean delivery. However, in cases of delayed transfer or if parturient was already in labor, only ultrasonography was done and considered as sufficient. Delivery was usually scheduled at 36 weeks of gestation. Patients were allocated into two group: Group TG in which a tourniquet was systematically applied on the lower segment of the uterus during emergent hysterectomy, control group CG when the emergent caesarian hysterectomy was performed without a tourniquet. Allocation depended on the technique and the decision of the surgeon in charge. After appropriate conditioning and monitoring, the cesarean section was performed under general anesthesia. The laparotomy was performed through a mid-line incision from the umbilicus to the pubic symphysis. Hysterotomy was made far from the placental insertion which was previously located by ultrasonography. The accretization was clinically checked immediately after delivery but no attempt was made to manually remove the placenta. The umbilical cord was ligated to its insertion and the uterus was quickly sutured with the placenta kept in place. Careful detachment of the bladder-uterus peritoneum was then carried out in order to lower the bladder and reduce the risk of bladder wounds. Tourniquet application procedure is described as following 1. Suturing hysterotomy with placenta kept in place. 2. After a cautious dissection a Folley catheter is placed in the lower segment of the uterus as tourniquet. 3. complete hysterectomy

Interventions

PROCEDURETourniquet: Folley catheter in the low segment of the uterus

Sponsors

University Tunis El Manar
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

* . All patients undergoing scheduled or emergency cesarean section for placenta accreta

Exclusion criteria

* No signs of accretetization upon artificial delivery

Design outcomes

Primary

MeasureTime frameDescription
Intensive care transfer ratefirst 24 hoursIntensive care transfer following hysterectomy for placenta accreta
Estimated blood lossperoperativelyBlood spoliation during procedure
Hemoglobin variationFirst 24 hoursthe differnece between the Baseline concentration of Hemoglobin and the lowest hemoglobin concentration noted during the procedure
Transfusion requirementsFirst 24 hoursNumber of red blood cells units transfused
procedure durationperoperativelyTime needed to perform hysterectomy from incision to skin closure

Secondary

MeasureTime frameDescription
clotting disorderstime from surgery up to 30 days postoperativeAssessed by the incidence of Intravascular disseminated coagulopathy
Bladder woundtime from surgery up to 30 days postoperativeIncidence of accidental bladder damage
Digestive woundtime from surgery up to 30 days postoperativeIncidence of accidental digestive lesion
length of stay in ICUtime from surgery up to 30 days postoperativeduration of the stay in the ICU following hysterectomy for placenta accreta

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026