Comparison of Environmental Factors Between the Areas of Over- and Under-incidence of Crohn's Disease in the Haut de France Region, by the Study of Dental Exposomes

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03706196

Acronym

EXPOSOMES

Enrollment

Registered

2018-10-15

Start date

2019-04-02

Completion date

2019-07-16

Last updated

2025-12-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Environmental Exposure

Keywords

dental exposome

Brief summary

the aim of this preliminary observational study is to compare external exposomes from 10 teeth issued through 10 subjects living in high incidence of crohn's disease area and 10 teeth issued through 10 subjects living in low incidence of crohn's disease area.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* adults subjects living in high and low incidence of crohn's disease areas and needing a dental extraction for medical indication

Exclusion criteria

* smokers during 10 last years

Design outcomes

Primary

Measure	Time frame
comparison of aluminum rate using metabolomic method in teeth between subjects living in high and low incidence crohn's disease areas.	Baseline: one session

Secondary

Measure	Time frame
comparison of environmental exposomes using metabolomic method in teeth between subjects living in high and low incidence crohn's disease areas.	Baseline: one session

Countries

France

Outcome results