The Impact of Physical Activity on the Postoperative Symptoms, Complications, and Quality of Life Among Lung Cancer

The Impact of Physical Activity on the Postoperative Symptoms, Complications, and Quality of Life Among Lung Cancer Survivors: A Prospective Cohort Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03705546

Enrollment

1050

Registered

2018-10-15

Start date

2016-03-04

Completion date

2026-03-03

Last updated

2024-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Neoplasms

Brief summary

The purpose of this study is to examine the impact of physical activity on the postoperative symptoms, complication, and quality of life.

Detailed description

Non-small cell lung cancer (NSCLC) survivor is increasing as developing early diagnosis and perioperative management. Despite multidisciplinary treatment, Surgery is the primary treatment option for cure in NSCLC. The patients with lung cancer who underwent surgery have limitation of pulmonary function and high risk of co-morbidities. Perioperative physical activity has been shown to reduce symptoms and prevent complications, improve long term quality of life after surgery. But validated exercise regimen has not been established for lung cancer patients. Therefore, Evidence-based guideline focusing on lung cancer after surgery is needed.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients who are diagnosed with lung cancer * Patients who are able to walk with ECOG (Eastern Cooperative Oncology Group) performance status \< 1 * Patients who understand the purpose of this study and provide the written informed consent

Exclusion criteria

* Patients who have difficulty for walking * Patients with history of other cancer in the last 3 years * Patients with neoadjuvant chemotherapy and/or radiation therapy * Patients who are diagnosed with recurrent lung cancer or multiple cancer * Foreigner of patients from overseas who are not able regularly participate in this study

Design outcomes

Primary

Measure	Time frame	Description
The change of quality of life: (EORTC QLQ) core30 (C30)	Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery	The change of quality of life is measured using the European Organization for Research Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ) core30 (C30). The scale for quality of life is transformed into a score from 0 to 100, derived by 4-point Likert scale. A higher score represents a higher level of quality of life.

Secondary

Measure	Time frame	Description
Postoperative pulmonary complications	Within 30 days after surgery	Incidence of pulmonary complications including air leak, atelectasis, pleural effusion, pneumonia, etc.
The change of symptom	Before surgery (baseline), and 1, 6, 12, 24, 36, 48, and 60 months after surgery	The change of symptom is measured using the European Organization for Research Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ) lung cancer module 13 (LC13). The scale for symptom is transformed into a score from 0 to 100, derived by 4-point Likert scale. A higher score represents a higher level of symptom.

Countries

South Korea

Outcome results