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Behavioral Economics Applications to Geriatrics Leveraging EHRs

Behavioral Economics Applications to Geriatrics Leveraging EHRs

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03704389
Acronym
BEAGLE R21
Enrollment
664
Registered
2018-10-12
Start date
2019-01-17
Completion date
2019-08-18
Last updated
2025-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asymptomatic Bacteriuria, Prostate Specific Antigen, Type 2 Diabetes Mellitus

Keywords

Geriatrics, Clinical decision support, Behavioral Economics

Brief summary

The risks and benefits of many diagnostic approaches and treatments differ for older adults compared to middle aged adults. When diagnostic and therapeutic strategies are misapplied to older adults this can lead to increased morbidity and mortality. Well established examples where clinicians do not often follow best practices in the care of older adults include those identified by the American Geriatrics Society for the Choosing Wisely initiative: 1) testing and treatment for asymptomatic bacteriuria, 2) prostate specific antigen testing in older men without prostate cancer, and 3) overuse of insulin or oral hypoglycemics for type 2 diabetes. Clinical decision support nudges, informed by social psychology and delivered via electronic health records (EHRs), are promising strategies to reduce the misuse of services in cases where optimal utilization may not be zero but should be well below current practice. These interventions seek to influence conscious and unconscious drivers of clinical decision making, are low cost to implement and disseminate, and can be incorporated into existing delivery systems. In the R21 phase of this Behavioral Economics Applications to Geriatrics Leveraging EHRs (BEAGLE) study, we will: select EHR delivered nudges to address 3 topics of potential misuse in older adults based on the main psychological drivers of overuse identified in interviews with high-using clinicians; develop and pilot test decision support tools within a health systems' EHR to understand technical feasibility, work flow fit, preliminary impact on clinical outcomes, and clinician acceptability; and develop and validate electronic clinical quality measures of potential overuse/misuse related to the care of older adults.

Detailed description

The risks and benefits of many diagnostic approaches and treatments differ for older adults compared to middle aged adults. When diagnostic and therapeutic strategies are misapplied to older adults this can lead to increased morbidity and mortality. Well-established examples where clinicians do not often follow best practices in the care of older adults include those identified by the American Geriatrics Society for the Choosing Wisely initiative: 1) testing and treatment for asymptomatic bacteriuria, 2) prostate specific antigen testing in older men without prostate cancer, and 3) overuse of insulin or oral hypoglycemics for type 2 diabetes. There are several hypotheses as to why clinicians fail to incorporate best evidence into geriatric clinical care. First, they may underestimate downstream harms of testing which seems easy to do (e.g., a urinalysis for a non-specific symptom) or treatment that may be appropriate for younger patients (e.g. intensifying insulin to achieve tight control). Second, clinicians may overweigh the risks of not performing the action (e.g., missing cancer diagnosis, failing to diagnose urinary tract infection (UTI) in a patient presenting without urinary tract symptoms). Third, clinicians may respond to real or perceived social norms (from patients and their families, other clinicians or both) that set expectations to behave in specific ways. Fourth, force of habit may lead clinicians to act in a way similar to how they have done in the past even if current evidence doesn't support it. And fifth, clinicians may overuse a test or treatment to avoid feeling they are expressing an ageist bias toward their patients. Clinical decision support nudges, informed by social psychology and delivered via electronic health records (EHRs), are promising strategies to reduce the misuse of services in cases where optimal utilization may not be zero but should be well below current practice. These interventions seek to influence conscious and unconscious drivers of clinical decision making, are low cost to implement and disseminate, and can be incorporated into existing delivery systems. In the R21 phase of this Behavioral Economics Applications to Geriatrics Leveraging EHRs (BEAGLE) study, we will: select EHR delivered nudges to address 3 topics of potential misuse in older adults based on the main psychological drivers of overuse identified in interviews with high-using clinicians; develop and pilot test decision support tools within a health systems' EHR to understand technical feasibility, work flow fit, preliminary impact on clinical outcomes, and clinician acceptability; and develop and validate electronic clinical quality measures of potential overuse/misuse related to the care of older adults.

Interventions

BEHAVIORALClinical decision support

Clinical decision support nudges within the electronic health record

Sponsors

University of California, Los Angeles
CollaboratorOTHER
University of Southern California
CollaboratorOTHER
National Institute on Aging (NIA)
CollaboratorNIH
Northwestern University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Northwestern Medicine primary care clinician caring for adults * Provides informed consent

Design outcomes

Primary

MeasureTime frameDescription
Misuse of Urinalysis or Urine Culture in Older Women6 months intervention periodPercentage of women patients aged 65 years and older who underwent a urinalysis and/or urine culture for suspected urinary tract infection (UTI) who did not have genitourinary specific symptoms
Prostate-Specific Antigen (PSA) Testing in the Elderly6 month intervention periodPercent of male patients seen by participating clinicians 76 and older with no history of prostate cancer who had a PSA test done during the measurement period
Diabetes Overtreatment in the Elderly6 month intervention periodPercent of diabetes patients 75 and older treated with insulin or oral hypoglycemic with hemoglobin A1c less than 7.0.

Countries

United States

Participant flow

Recruitment details

All study outcome data are from patients. We report on the n=664 patients who were attributed to a study clinician with a visit during the intervention period that met denominator criteria for an outcome.

Pre-assignment details

This is a small non-randomized pilot study. This trial enrolled patients with a waiver of informed consent. Clinicians were not enrolled. All outcome data were collected via the electronic health record. This explains why the number of participants started is the same as the number of participants completed.

Participants by arm

ArmCount
Clinical Decision Support Intervention
Participating clinicians will receive any of three clinical decision support nudges within the electronic health record when all eligibility criteria are met within a patient's chart. Clinical decision support: Clinical decision support nudges within the electronic health record Baseline characteristics were not collected from enrolled clinicians.
664
Total664

Baseline characteristics

CharacteristicClinical Decision Support Intervention
Age, Categorical
<=18 years
0 Participants
Age, Categorical
>=65 years
664 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
Race and Ethnicity Not Collected— Participants
Region of Enrollment
United States
664 Participants
Sex: Female, Male
Female
230 Participants
Sex: Female, Male
Male
308 Participants

Adverse events

Event typeEG000
affected / at risk
deaths
Total, all-cause mortality
0 / 664
other
Total, other adverse events
0 / 664
serious
Total, serious adverse events
0 / 664

Outcome results

Primary

Diabetes Overtreatment in the Elderly

Percent of diabetes patients 75 and older treated with insulin or oral hypoglycemic with hemoglobin A1c less than 7.0.

Time frame: 6 month intervention period

Population: Percent of diabetes patients 75 and older treated with insulin or oral hypoglycemic with hemoglobin A1c less than 7.0.

ArmMeasureValue (COUNT_OF_PARTICIPANTS)
Clinical Decision Support InterventionDiabetes Overtreatment in the Elderly50 Participants
Primary

Misuse of Urinalysis or Urine Culture in Older Women

Percentage of women patients aged 65 years and older who underwent a urinalysis and/or urine culture for suspected urinary tract infection (UTI) who did not have genitourinary specific symptoms

Time frame: 6 months intervention period

Population: Proportion of female patients aged 65 years and older with a primary care encounter who had a urinalysis or urine culture done for non-specific reasons among those with a test done

ArmMeasureValue (COUNT_OF_PARTICIPANTS)
Clinical Decision Support InterventionMisuse of Urinalysis or Urine Culture in Older Women25 Participants
Primary

Prostate-Specific Antigen (PSA) Testing in the Elderly

Percent of male patients seen by participating clinicians 76 and older with no history of prostate cancer who had a PSA test done during the measurement period

Time frame: 6 month intervention period

Population: Percent of male patients seen by participating clinicians 76 and older with no history of prostate cancer who had a PSA test done during the measurement period

ArmMeasureValue (COUNT_OF_PARTICIPANTS)
Clinical Decision Support InterventionProstate-Specific Antigen (PSA) Testing in the Elderly13 Participants

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026