Diffuse Parenchymal Lung Diseases
Conditions
Keywords
Transbrochial cryobiopsy, Diffuse parenchymal lung diseases, Diagnosis
Brief summary
The Diagnostic yield and Safety of transbronchial cryobiopsy in the diagnosis of diffuse parenchymal lung diseases are investigated in this multicenter, prospective and real world study.
Interventions
PROCEDURETransbronchial cryobiopsy
Transbronchial cryobiopsy procedure
Sponsors
Guangzhou Institute of Respiratory Disease
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. The patients are admitted in the institution as DPLD, while undefined after thorough history collection, laboratory examination and radiological data. 2. Transbronchial cryobiopsy(TBCB) is indicated by clinicians for definitive diagnosis and patients are content with the examination with agreement signed. 3. Blood gas analysis, routine blood test, ECG examination, coagulation function, immunological examination, chest HRCT, and liver/kidney function test have been completed.
Exclusion criteria
1. The radiological data indicates non-DPLD 2. The clinical examinations mentioned above are not completed. 3. The patient cannot endure or does not agree the procedure.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnotic yield | two weeks | Percentage of definitive pathological diagnosis by transbronchial cryobiopsy, the alteration of original diagnosis after transbronchial cryobiopsy |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Complication rate | 12 weeks | Incidence of bleeding, pneumothorax (during the procedure and within 7 days after the intervention) and exacerbations of DPLD related to the transbronchial cryobiopsy (in 12 weeks). |
Countries
China
Contacts
Primary ContactShiyue Li
Backup ContactXiaobo Chen
Outcome results
None listed