Oxytocin Infusion and Abdominal Myomectomy

Effect of Oxytocin Infusion on Reducing the Blood Loss During Abdominal Myomectomy: A Randomized Controlled Trial

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03702946

Enrollment

Registered

2018-10-11

Start date

2017-07-15

Completion date

2018-01-15

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oxytocin and Abdominal Myomectomy

Brief summary

Objective:To compare oxytocin infusion with control, in patients undergoing abdominal myomectomy in terms of mean blood loss. Design: Single blinded randomized control trial Setting: Obstetrics and Gynecology Department, Military Hospital, Rawalpindi Population: 60 women of ASA class I-II, with intramural fibroids, candidate for elective abdominal myomectomy. Methods: Women were divided into two groups randomly. In the study group 30 Units of oxytocin in 1000 ml normal saline were given during surgery, at the rate of 15units/hour. In control group, pure normal saline was given. Main outcome measure: Intra-operative blood loss

Interventions

OTHERoxytocin in abdominal myomectomy

Women were divided into two groups randomly. In the study group 30 Units of oxytocin in 1000 ml normal saline were given during surgery, at the rate of 15units/hour. In control group, pure normal saline was given

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 40 Years

Healthy volunteers

Inclusion criteria

1. women of ASA class I-II with intramural fibroids, 2. women planned to undergo elective abdominal myomectomy

Exclusion criteria

1. Women with hemoglobin (Hb) \< 10g/dl 2. Women with any respiratory or cardiovascular disease.

Design outcomes

Primary

Measure	Time frame	Description
Intra-operative blood loss	during the surgical procedure	average intra operative blood loss was measured

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026