Vascular Dementia
Conditions
Brief summary
Individuals with uncontrolled vascular disease are at risk for an insidious progression of brain injury starting in early to midlife and ultimately culminating in a vascular dementia, robbing them of activities of daily living independence. Successful containment of this progression requires rigorous vascular risk factor management - the control of blood pressure, blood sugars, weight, and alcohol consumption; the cessation of smoking, and an increase in aerobic activity. SymTrend's mobile and web system for managing vascular risk factors will help improve adherence to health and lifestyle strategies, will stem cognitive decline, and will preserve independence in the community for older adults.
Detailed description
Neurologists from Massachusetts General Hospital will refer 10 adults with vascular mild cognitive impairment for participation in this project. The patients will be given Bluetooth devices appropriate for their condition and will be trained to use SymTrend and Apple Health software. They will use the software and devices for three months; will receive messages throughout from the system and/or a research coordinator about their progress, with encouragement and strategies to fully manage their symptoms; and their neurologist will be in communication with them about the progress charts and will adjust their care on the basis of this real-time data.
Interventions
BEHAVIORALSymTrend, Inc.
Use of SymTrend and Apple Health apps with feedback and strategies provided.
Sponsors
National Institute on Aging (NIA)
Massachusetts General Hospital
SymTrend Inc.
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Intervention model description
In this feasibility study, a customized electronic diary will be provided to collect data 1) from bluetooth devices, 2) from Apple Health app information, and 3) from self-reported diary information. Researchers will provide feedback via charts and reminders/text messages to encourage management of vascular risk factors.
Eligibility
Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Prior incidence of neurological event such as transient ischemic attack, stroke.
Exclusion criteria
* Inability to use smartphone, * Inability to read English
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reduced smoking | three months | Number of cigarettes smoked is reduced or eliminated |
| Improved management of blood sugar | three months | Blood sugars are measured regularly and are maintained within bounds prescribed by MD |
| Improved blood pressure management | three months | Blood pressure is measured regularly and is within bounds prescribed by MD |
| Weight is reduced if necessary | three months | Food intake is reduced and is healthier, and as a consequence weight is reduced |
| Activity level is increased | three months | Step count increases continuously throughout study period |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fatigue is reduced if originally is a problem | three months | Hours sleep increases and frequency of sleep interruption reduces |
Countries
United States
Contacts
Primary ContactMinna Levine, Phd
Outcome results
None listed