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Uterine Artery Doppler Changes Prior and After Breastfeeding

Postpartum Uterine Artery Doppler Changes Prior and After Breastfeeding

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03701633
Enrollment
500
Registered
2018-10-10
Start date
2018-11-01
Completion date
2020-03-01
Last updated
2018-12-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breastfeeding

Brief summary

We aim to determine whether there are any differences in the UtA doppler measurements in postpartum women prior and right after breastfeeding.

Detailed description

There is emerging evidence linking abnormal UtA Doppler indices in the postpartum period as a risk factor for developing future cardiovascular disorders. Thus far, no study considered the postpartum physiology itself as a possible confounder. If one wishes to draw conclusions about future cardiovascular risk, the role of oxytocin as a confounder must be determined. In the current study, we aim to determine whether oxytocin, physiologically produced during breastfeeding, has an effect on the UtA Doppler measurements in the postpartum period.

Interventions

DIAGNOSTIC_TESTPostpartum ultrasound

Measurements of the UtA doppler ultrasound will be carried out twice for each eligible woman on the second day postpartum. The first measurement will take place just prior to a planned breastfeeding. The second measurement will be followed immediately (within 10 min) after the breastfeeding session.

Sponsors

Rambam Health Care Campus
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
Yes

Inclusion criteria

-Every woman who had vaginal delivery, instrumental delivery or cesarean section.

Exclusion criteria

-Patient's refusal, women who decided not to breastfeed, women who wish to breastfeed, but in whom no milk production commenced yet.

Design outcomes

Primary

MeasureTime frameDescription
Postpartum uterine artery doppler changes prior and after breastfeeding.One yearTo determine whether there are any differences in the UtA doppler measurements in postpartum women prior and right after breastfeeding.

Countries

Israel

Contacts

Primary ContactYaniv Zipori, M.D
y_zipori@rambam.health.gov.il+972 58 7966963

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026