Comparison Between Two Different Protocols of Negative Pressure Therapy for Healing of Chronic Ulcers

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03701152

Enrollment

Registered

2018-10-09

Start date

2018-01-01

Completion date

2018-12-01

Last updated

2018-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Ulcers, Negative Pressure Therapy

Brief summary

Negative Pressure Wound Therapy (NPWT), is a non invasive wound management tool which develops from negative pressure being applied to the wound. This promotes healing through the removal of infectious materials and enhancing granulation tissue formation. NPWT eases debridement as well as promoting healing of different types of wounds.

Detailed description

Assessment of wound surface area was done by a graded plastic sheet and a metric graph paper, by counting the complete squares of the metric graph paper, while the wound size was done by using a 10 cm syringe filled with dermazin cream and filling the wound with it. Negative pressure device: VAC system 125mmhg (KCI negative pressure equipment). Wound surface area tracing tools: * Sterilized transparent film. * Fine tipped transparent marker. * Carbon and a white A4 papers. * Metric graph paper (1mm²). Wound volume assessment procedure: * Using a syringe of ten cubic centimeters filled with dermazin cream. * The wound is filled with the cream * The amount of cream injected into the wound was detected in cubic centimeters.

Interventions

DEVICENegative pressure therapy

Negative pressure therapy at sub atmospheric level

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

27 Years to 65 Years

Healthy volunteers

Inclusion criteria

* They were free from immune deficiency diseases or collagen diseases. * All patients were homeostasis. * All patients were medically stable. * All cases were chronic and did not heal with other treatment methods

Exclusion criteria

* 1\. Malignancies or receiving radiotherapy. 2. Dermatological diseases. 3. Deep venous thrombosis. 4. Renal failure. 5. Immunosuppressant or anticonvulsants therapies.

Design outcomes

Primary

Measure	Time frame
Wound surface area	8 weeks
Wound size	8 weeks

Countries

Egypt

Contacts

Primary ContactAshraf Hassan, phD

ashraf.hassan@buc.edu.eg+2001067302580

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 1, 2026