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4-choice Reaction Time Test for the Measurement of Psychomotor Recovery After General Anaesthesia

Computerised 4-choice Reaction Time Test for the Measurement of Psychomotor Recovery After General Anaesthesia

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03697057
Acronym
4CRT_Ane
Enrollment
166
Registered
2018-10-05
Start date
2008-03-31
Completion date
2010-04-30
Last updated
2018-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Complications

Keywords

postoperative recovery, psychomotor function, measurement

Brief summary

The recovery of patients after general anaesthesia is usually estimated by using clinical signs and scores. Since there is a lack of the agreed objective methods for assessing cognitive and psychomotor recovery after general anaesthesia in ambulatory settings, the aim of this study was to evaluate three psychological tests for this purpose. Patients, who were scheduled for ambulatory gynaecological surgery, underwent 3 standard psychological tests before (T1), 15 minutes after the surgery (T2) and on discharge from the recovery room (T3). The tests used were Wechsler memory scale (test 1, working memory capacity), d2 - test (test 2, concentration endurance) and computer-based 4-choice-reaction time (4CRT, test 3, reaction time) as well as Postanesthesia Discharge Scoring System (PADSS). The same test battery was used in healthy female volunteers, all test results were compared at the different time points.

Interventions

PROCEDUREGeneral anaesthesia

Standard general anaesthesia for gynecologic surgery in patient group

Sponsors

University Medicine Greifswald
Lead SponsorOTHER

Study design

Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* consecutive patients scheduled for ambulatory gynaecologic surgery * age of 18 to 60 years * a physical status I-II according to American Society of Anesthesiologists (ASA) classification * fluency in German language and the ability to perform all tests

Exclusion criteria

* chronic consume of analgesics, psychotropic drugs, sedatives or alcohol * if the ambulatory surgery lasted more than 60 minutes * if the schema of standardised general anaesthesia was changed * if the ambulatory setting was changed and the patients unexpectedly remained over night in the hospital.

Design outcomes

Primary

MeasureTime frameDescription
4CRT_15_min15 minutes after the end of surgeryChange of four choice reaction time (4CRT) at 15 minutes after surgery from baseline

Secondary

MeasureTime frameDescription
PADSS (Patient Discharge Scoring System)Measured 60 minutes after the end of surgeryPost Anaesthetic Discharge Scoring System (PADSS) is a clinically-based, objective scoring system used to measure the home readiness of patients following day surgery. PADSS consists of six criteria: ambulation, circulation (blood pressure monitoring), nausea/vomiting, pain and surgical bleeding bleeding. Each criterion is given a score ranging from 0 to 2, maximal score is 10. Only patients who achieve a score of 9 or more are considered ready for discharge.

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026