Gingival Recession
Conditions
Keywords
advanced platelet rich fibrin,A-PRF
Brief summary
patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate while the intervention one will have coronally advanced flap with advanced platelet rich fibrin(A-PRF).as it represent a new generation of platelet concentrate allow for better healing and root coverage results. Null hypothesis: In patients with Miller class I and II gingival recession, there is no difference in amount of root coverage (mm) following the application of SCTG+A-PRF compared to CAF+SCTG.
Detailed description
* Population (P): Patients with single Miller class I, II gingival recessions. * Intervention (I): Coronally advanced flap (CAF) plus platelet rich fibrin (A-PRF). * Comparator (C): Coronally advanced flap (CAF) plus subepithelial connective tissue graft (SCTG). * Primary Outcome (O): Root coverage (mm). * Time frame: 9 months. * Study design: Randomized controlled clinical trial. * Patients are to be selected from the outpatient clinic of the department of Oral Medicine and Periodontology-Cairo University
Interventions
PROCEDURECAF + (A-PRF)
advanced platelet rich fibrin prepared by low speed centrfugation concept(LSCC) together with coronally advanced flap .
PROCEDURECAF+SCTG
cornally advanced flap plus subepithilial connective tissue graft harvested from the palate
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Systemically healthy patients 18 years old and older both males and females. * Good oral hygiene after phase I therapy. * Miller's class I or II gingival recession. * Not using antibiotics, steroids, chemotherapy or other medications that may modify results of the surgery and healing. * Cooperative patients able and accept to come for follow up appointments
Exclusion criteria
* Pregnant or lactating females. * Current Smokers. * Patients with any systemic disease that may affect the periodontal healing. * Teeth with endodontic treatment, buccal restoration or caries. * Patients with poor oral hygiene
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| root coverage | 9 months | measured in millimeter |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Recession width | 9 months | measured in millimeter |
| Clinical attachment level | 9 months | measured in millimeter |
| Width of keratinized gingiva | 9 months | measured in millimeter |
| Probing depth | 9 months | measured in millimeter |
| Gingival esthetics | 9 months | Root coverage esthetic score |
| Post-operative pain | measured daily for the first 2 weeks post- operatively. | Visual analog scale (VAS) Questionnaire |
| Patient Satisfaction | 9 months | Post-Surgical Patient Satisfaction Questionnaire |
| Early wound healing | 1,2,4 weeks post- surgical | Early wound healing index |
| Gingival thickness | 9 months | measured in millimeter |
Contacts
Primary Contactheba samir mahmoud, assistant lecturer
Outcome results
None listed