Sarcopenia
Conditions
Keywords
sarcopenia, vibration, gait, muscle, rehabilitation
Brief summary
Sarcopenia is defined as a phenomenon which the amount of muscle mass in elderly aged 60-70 years is about 20-30% lower than that of the young adults and middle-aged people due to muscle atrophy caused by aging and alteration in muscle itself in aged skeletal muscle. Whole body vibration(WBV) training can be a choice for hospitalized patients who cannot conduct high intensity resistance training.
Detailed description
This study is prospective study. The goal of this study is 1. To investigate the effect of whole body vibration training using vibration platform with tilt table on muscle mass, muscle strength, physical performance in hospitalized older adults with sarcopenia. 2. To demonstrate whether whole body vibration training using vibration platform with tilt table can be useful in hospitalized older adults with sarcopenia who could not perform high intensity exercise.
Interventions
DEVICEwhole body vibration plus conventional therapy
Subjects enrolled in whole body vibration training group are exposed to side-to-side alternating vertical sinusoidal vibration. Galileo system(Novotec Medical GmbH, Pforzheim, Germany) is used to training. Frequency of whole body vibration is 12Hz and amplitude is 4mm. After 10 minutes of vibration training, subjects rest 3 minutes. Then, additional 10 minutes of training will be given. conventional physical therapy is consisted of passive range of motion exercise and walking exercise.
PROCEDUREconventional therapy
conventional physical therapy is consisted of passive range of motion exercise and walking exercise.
Sponsors
Seoul National University Bundang Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
70 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* More than 70-year old people who admitted Seoul National University hospital, Bundang. * Deconditioning subjects with diabetics, infections, chronic lung disease, etc. who cannot walk independently due to long-term hospital care. * Subjects who had a mobility impairment. * Subjects who can agree voluntarily.
Exclusion criteria
* Subjects who inserted implant due to trauma within 1\ 2 months recently. * Acute coronary syndrome. * Uncontrolled hypertension. * Subjects who took drugs which can affects neuromuscular system. * Severely impaired cognition * Subjects who cannot agree volun.tarily.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Berg balance scale | Before intervention / after two weeks intervention | Change from baseline Berg balance scale to 2 weeks after initial assessment. Berg balance scale \[from 0 to 56 score\] is widely used to assess subjects' ability to control body balance. For '0' score, it means subject cannot maintain his/her own standing balance. For '56' score, he/she can properly keep static/dynamic standing balance. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Maximal voluntary isometric contraction at knee | Before intervention / after two weeks intervention | Change from baseline knee extension power to 2 weeks after initial assessment. Using the machine(muscle tester(manual), Lafayett instrument, USA), knee extension power will be measured while subject sit in the chair. |
| 10 meter walking test | Before intervention / after two weeks intervention | Change from baseline time when performing 10 meter walking test to 2 weeks after initial assessment. The subject was asked to move 10 meter away from baseline. While subject moved, total amount of time was measured. Then, the time used in first 2 meter movement and last time used in last 2 meter movement was excluded. Finally, total time used in 6 meter movement was measured. |
| Hand grip muscle strength | Before intervention / after two weeks intervention | Change from baseline hand grip strength to 2 weeks after initial assessment. Its assessment is made by Leonardo Mechanograph(Novotec Medical GmbH, Pforzheim, Germany), (unit = N ). For the actual testing procedure, grip strength measurements of the bilateral limb were conducted. The subject was instructed to slowly squeeze the machine. Each measure site was tested one times during 3 seconds. The subjects sit in the chair, maintaining elbow flexed at 90 degree. |
Countries
South Korea
Contacts
Primary ContactJae-Young Lim, Ph.D.
Backup ContactBo-Ram Kim
Outcome results
None listed