Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients

Dépistage Des métastases cérébrales Par IRM Chez Les Patients Avec un adénocarcinome Colorectal métastatique

Status

Active, not recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03694938

Enrollment

143

Registered

2018-10-03

Start date

2019-02-07

Completion date

2030-02-28

Last updated

2025-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metastatic Colon Cancer

Keywords

Brain metastasis, Magnetic resonance imaging

Brief summary

The aim of this study is to prospectively determine the incidence of brain metastases in metastatic colorectal cancer patients using systematic annual screening by MRI.

Interventions

DEVICEMagnetic resonance imaging

Annually magnetic resonance imaging

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with histologically proven colorectal adenocarcinoma * Metastases from colorectal cancer diagnosed since less than 6 months * Indication of an oncologic treatment

Exclusion criteria

* Patient with contraindication for MRI * Diagnosis of cancer other than colorectal cancer in the last three years, except in situ cancers, basal-cell skin cancer or squamous-cell skin cancer, and other cancer with low risk of brain dissemination according to the investigator * Pregnant or breastfeeding women, women of childbearing potential without effective contraception

Design outcomes

Primary

Measure	Time frame	Description
Prospectively determine the incidence of brain metastases in metastatic colorectal cancer patients with annual MRI.	3 years	Diagnostic of brain metastases on annual MRI

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026