Functional Residual Capacity Measured by Capnography in Ventilated Patients

Effect of Positive End-expiratory Pressure on Functional Residual Capacity Measured by Volumetric Capnography in Mechanically Ventilated Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03693352

Enrollment

Registered

2018-10-03

Start date

2018-10-01

Completion date

2020-04-01

Last updated

2020-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Physiological Phenomena

Brief summary

Changes in body position during anesthesia can alter functional residual capacity and gas exchange. The monitoring of such changes in functional residual capacity is difficult at the bedside. The present study was designed to determine if volumetric capnography can detect changes in the functional residual capacity during surgery.

Detailed description

This is a prospective and observational study designed to test the reliability of the capnodynamic equation to determine changes in functional residual capacity measured during anesthesia. The investigators will studied 40 mechanically ventilated patients undergoing general anesthesia. Functional residual capacity will be continuously measured in a non invasive way using expired carbon dioxide. Changes in functional residual capacity with standard modification in body positioning (Trendelenburg or anti-Trendelenburg position) and ventilatory settings wiil be tested.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

30 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Written Inform Consent * Programmed surgery * Laparoscopic surgery * Supine position

Exclusion criteria

* Emergency surgery * Chronic respiratory disease * Active smoking

Design outcomes

Primary

Measure	Time frame	Description
Functional Residual Capacity Measured by Capnography in Ventilated Patients	6 hours	Measurement of functional residual capacity with capnography with body positioning changes.

Countries

Argentina

Outcome results