Postoperative Pain
Conditions
Brief summary
To assess the Postoperative Pain after using Silver Nanoparticles with and without Calcium Hydroxide as an Intracanal Medication in Patients with necrotic pulp (RCT)
Detailed description
When the treatment itself appears to initiate the onset of pain and/or swelling, the result can be very distressing to both the patient and the operator. Patients might even consider postoperative pain and flare-up as a benchmark against which the clinician's skills are measured. Prevalence of postoperative pain or flare-up is, therefore, one of the influencing factors when making a clinical decision. Better management of postoperative pain increases the patients' confidence in dentist's skills and gives positive attitude toward dental profession. In cases with necrotic pulp, the incidence of pain becomes higher, hence testing which intracanal medication is more effective in decreasing the bacteria present within the root canal and subsequently pain is crucial.
Interventions
COMBINATION_PRODUCTSilver nanoparticle/Calcium hydroxide
Intracanal Medication composed of combined silver nanoparticles with calcium hydroxide
DRUGSilver Nanoparticles in gel form
Intracanal medication composed of silver nanoparticles in gel form
Calcium hydroxide intracanal medication
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients who are free from any physical or mental handicapping condition with no underlying systemic disease. * Non-pregnant females * Asymptomatic necrotic mandibular single rooted teeth. * Normal occlusal contact with the opposing teeth. * Patients accepting to participate in the study.
Exclusion criteria
* Medically compromised patients: Pain levels and healing following treatment would be compromised as these patients have shown higher incidence of pain and lower healing rate. * Pregnant women: Avoid radiation exposure, anesthesia, and medication. * If analgesics or antibiotics have been administrated by the patient during the past 12 hours preoperatively might alter their pain perception * Patients reporting bruxism or clenching: Avoid further pressure on an already inflamed tooth inducing subsequent irritation and inflammation Teeth that shows: * Association with acute periapical abscess and swelling: Need special treatment steps which could involve additional visits with incision and drainage. Also, it could influence initiation and progression of postoperative pain. * Greater than grade I mobility or pocket depth greater than 5mm. Need special surgical and/or periodontal therapy. * No restorability: Hopeless tooth. * Vital teeth * Immature teeth * Radiographic evidence of external or internal root resorption. * Any criterion, not mentioned in the inclusion criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in post-operative pain | Intra-appointment and post obturation at 4, 24, 48, 72, 96 hours | Numerical (0-10) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intracanal Bacterial count reduction | 1 week | Quantification of Colony forming units per milliliter of agar medium (CFU/mL) |
| Number of analgesic tablets taken by the patient after endodontic treatment | Within 4 days after the first session and after 1 week from first treatment session | Number |
Countries
Egypt
Outcome results
None listed