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Association of the Optic Nerve Sheath Diameter With Eyeball Transverse Diameter in Robot-assisted Prostatectomy

Ultrasonographic Measurement of the Optic Nerve Sheath Diameter and Its Association With Eyeball Transverse Diameter in Robot-assisted Laparoscopic Radical Prostatectomy

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03691025
Enrollment
60
Registered
2018-10-01
Start date
2018-10-15
Completion date
2019-03-01
Last updated
2018-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elevated Intracranial Pressure, ONSD /ETD Ratio, Optic Nerve Sheath Diameter

Keywords

robot assisted laparoscopic prostatectomy, optic nerve sheath diameter

Brief summary

Robot-assisted laparoscopic radical prostatectomy (RALRP) is becoming a popular procedure due to its unique advantages. Despite these advantages, pneumoperitoneum and steep trendelenburg position are associated with hemodynamic instability and elevated intracranial pressures (ICP). Ultrasonographic measurement of optic nerve sheath diameter (ONSD) is an indirect but also a generally accepted reliable and noninvasive measurement of elevated ICP. However, optimal cut-off values are highly inconsistent due to multiple factors (gender, height, weight). To eliminate the effects of these factors on the results; a ratio should be established in patients known to have elevated ICPs. In a recent study ONSD/ eyeball transverse diameter(ETD) in healthy volunteers in a specific population was established. 60 patients without any history of ICP undergoing RALRP will be enrolled to the study. Ultrasonographic measurement of ONSD and ETD will be performed 10 minutes after induction of general anesthesia, 10 minutes after CO2 pneumoperitoneum with trendelenburg positioning and measurements will be repeated hourly and at last after returning to supine position without CO2 pneumoperitoneum at the end of the procedure. Hemodynamic variables and BIS values on this specific times will be recorded and an arterial sample will be obtained.

Interventions

None listed

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
18 Years to 75 Years

Inclusion criteria

* 19-75 years patients undergoing RALP

Exclusion criteria

* a history of corneal surgery, open-angle or closed-angle glaucoma * intraocular surgery * history of elevated ICPs

Design outcomes

Primary

MeasureTime frameDescription
Association of the Optic Nerve Sheath Diameter With Eyeball Transverse Diameter in Robot-assisted Prostatectomy6 monthsTo determine a cut off value for ratio of ONSD to ETD in a group known to have elevated ICPs

Contacts

Primary ContactBaşak Akça
drbasakakca@gmail.com00905322275451
Backup ContactBanu Kılıçaslan
banuk09oct@gmail.com00905322969290

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026