Bariatric Surgery, Lipidemia
Conditions
Brief summary
Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including type 2 diabetes. Laparoscopic gastric bypass surgery and laparoscopic sleeve gastrectomy are commonly used in bariatric surgery. Laparoscopic sleeve gastrectomy due to simple operation, good weight loss, and metabolic disease control effect, which is more widely used. However, there are several studies that show an increased chance of gastroesophageal reflux disease after laparoscopic sleeve gastrectomy. Long-term gastroesophageal reflux may lead to Barrett's esophagus or esophageal cancer. Nowadays, the cause of gastroesophageal reflux disease after sleeve gastrectomy is not clear and precautionary measures are not precise. In this study, prospective randomized controlled trials were conducted to explore the possible change of lipidemia after bariatric surgery and to explore ways to prevent bariatric surgery after bariatric surgery.
Interventions
PROCEDUREsleeve gastrectomy
sleeve gastrectomy.
PROCEDUREgastric bypass
gastric bypass
Sponsors
First Affiliated Hospital of Jinan University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
-For the choice of surgical approach, numerous studies have shown that BMI ≧ 45, the general choice of gastric bypass surgery, BMI \<45, you can choose sleeve gastrectomy. The remission rate for T2DM, sleeve gastrectomy has a good result for young patients with shorter duration. In the investigator's country, the BMI less than 45 is majorities.
Exclusion criteria
-BMI\<27.5
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative of choleaterol at 1 year | 1 year | choleaterol in ml/dl |
| preoperative of choleaterol | Preoperate | choleaterol in ml/dl |
| Postoperative of choleaterol at 3 months | 3 months | choleaterol in ml/dl |
| Postoperative of choleaterol at 6 months | 6 months | choleaterol in ml/dl |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Preoperative of triglyceride | Preoperative | triglyceride in ml/dl |
| Postoperative of triglyceride at 3 months | 3 months | triglyceride in ml/dl |
| Postoperative of triglyceride at 6 months | 6 months | triglyceride in ml/dl |
| Postoperative of triglyceride at 1 year | 1 year | triglyceride in ml/dl |
Countries
China
Outcome results
None listed