Migraine Aura
Conditions
Keywords
migraine aura
Brief summary
investigators hypothesize that T2 \* vein abnormalities are frequent and are specific to the migraine aura.
Detailed description
The diagnosis of migraine aura is now based solely on clinical criteria and the assertion of the diagnosis on these clinical criteria alone proves difficult in the acute phase. Added to this difficulty, the symptomatology of a migraine aura can sometimes be similar to that of a stroke, so a diagnosis can be poorly established, resulting in poor patient care. The possibility of making the positive diagnosis of migraine aura on a routine MRI sequence, T2 \*, would be an important advance for the management of these patients
Interventions
COMBINATION_PRODUCTMRI
Routine MRI with all the sequences performed for the management of acute neurological deficit in the Toulouse Neuro Vascular Unit (diffusion, FLAIR, T2 \*, vascular sequences (AngioRM and TOF) and perfusion).
DIAGNOSTIC_TESTMRI control
MRI with all the sequences performed for the management of acute neurological deficit in the Toulouse Neuro Vascular Unit (diffusion, FLAIR, T2 \*, vascular sequences (AngioRM and TOF) and perfusion)
telephone consultation
Sponsors
University Hospital, Toulouse
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged 18 to 55 years * Admitted to the Neuro-Vascular Intensive Care Unit for Acute Focused Neurological Symptoms and MRI * less than 4 hours 30 minutes after onset of symptoms if symptoms persist during admission * less than two hours after the disappearance of symptoms if the patient arrives asymptomatic * Affiliated to a social protection scheme. * Having given their informed consent
Exclusion criteria
* Patients with neurological signs pointing to vertebrobasilar localization (vertigo, diplopia) or with a disorder of consciousness * Presence of recent explanatory abnormalities on the MRI to make a diagnosis compatible with the initial neurological symptomatology (visible stroke in diffusion, cerebral hemorrhage, tumor, arteriovenous malformations). * Potential strong cause of stroke known or discovered at the arrival of the patient, in particular stenosis of a cervical or intracranial artery upstream of the cerebral zone may correspond to the symptoms and emboligenic heart disease type atrial fibrillation. * Pregnant women - Patients with a contraindication for MRI. * Patients benefiting from a system of legal protection (tutelage,
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| frequency of the presence of visible brain vein abnormalities | Day 0 | visible brain vein abnormalities on T2 \* sequences MRI , |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| perfusion parameters | Day 0 | in MRI , Overall visual assessment: presence or absence of hypoperfusion (presence or not in each anterior, middle and posterior territory) each lobe: Frontal, Temporal, Parietal, Occipital) |
| asymmetry of visualization of the 3 intracranial arteries in MRI | Day 0 | in MRI TOF |
Countries
France
Outcome results
None listed