Frail Elderly Syndrome
Conditions
Keywords
aging, whole body vibration, respiratory muscle training
Brief summary
Aging generates immune, muscular and functional changes. In the pre-frail elderly these changes may be increased and, therefore, preventive interventions are indicated to minimize the consequences of sarcopenia in this population. This study aims to evaluate the effects of a whole body vibration training associated with the training of inspiratory muscles on the inflammatory, muscular and body composition outcomes in pre-frail elderly women.
Interventions
OTHERWBV + IMT
The whole body vibration training will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 02 to 04 mm.The inspiratory muscle training will be performed through a device that provides inspiratory resistance.
OTHERWBV + IMTsham
The whole body vibration training will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 02 to 04 mm.The inspiratory muscle training sham will be performed through a device without inspiratory resistance.
OTHERWBVsham + IMTsham
Whole body vibration training will be performed through a vibrating platform coupled to a device that generates non-therapeutic low frequency vibration. The simulation of inspiratory muscle training will be performed through a device with no inspiratory resistance.
Sponsors
Universidade Federal de Pernambuco
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
60 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Elderly individuals able to walk without assistance * Good understanding to carry out the proposed tests, evaluated through the Mini Mental State Examination (MMSE).
Exclusion criteria
* Contraindication or difficulty to perform evaluation procedures * Users of medications that interfere with the cardiovascular and / or muscular system * Smokers * Neuromuscular or degenerative diseases * Pulmonary comorbidities * Heart diseases * Labyrinthitis.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory Muscle Strength and Resistance | Change from Baseline respiratory muscle strength and resistance at 3 months | Maximum Inspiratory and Expiratory Pressure will be evaluated through manovacuometer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Diaphragmatic thickness | Change from Baseline diaphragmatic thickness at 3 months | Ultrasound will to use to evaluate diaphragm thickness non-invasively in the zone of apposition during tidal breathing and with changes in lung volume. |
| Thickness of the quadriceps muscle | Change from Baseline thickness of the quadriceps muscle at 3 months | Ultrasound will be used to assess the thickness of the quadriceps muscle according to the pre-established protocol. |
| Diaphragmatic mobility | Change from Baseline diaphragmatic mobility at 3 months | During respiration to total lung capacity, measurement of the diaphragmatic excursion will be assessed by ultrasonography. |
| Body Composition | Change from Baseline body composition at 3 months | Body composition will be evaluated through bioimpedance balance |
| Inflammatory markers | Change from Baseline inflammatory markers at 3 months | Blood concentration of Interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha) and brain-derived neurotrophic factor (BDNF) will be assessed through blood plasma sample. |
Countries
Brazil
Outcome results
None listed